International CIDP Outcome Study A prospective study on clinical and biological predictors of disease course and outcome in CIDP
Recruiting
- Conditions
- Chronic inflammatory demyelinating polyneuropathy1000381610034606
- Registration Number
- NL-OMON44925
- Lead Sponsor
- eurologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 225
Inclusion Criteria
1. The ICOS is using the EFNS/PNS criteria (clinical and electrophysiological criteria) for the diagnosis of CIDP.
Three categories of patients are eligible for the ICOS:
a) Patients fulfilling the clinical criteria and the definite, probable or possible electrophysiological criteria defined in supplement 1.
b) Patients fulfilling the clinical criteria and at least two supportive criteria defined in supplement 1.
c) Patients fulfilling the clinical criteria for pure sensory CIDP and at least two supportive criteria defined supplement 2 (if not fulfilling the electrophysiological criteria).
2. Being able and willing to conduct a follow-up of at least 2 years.
3. Informed consent.
Exclusion Criteria
No exclusion criteria
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>ICOS will result in a combined data- and biobank of well defined patients with<br /><br>CIDP.<br /><br>The primary study parameters will include the grip strength measured by using a<br /><br>Vigorimeter or Jamar dynamometer and the Rasch-MRC sum score. Furthermore we<br /><br>will use several standardized validated clinical outcome measure scales such<br /><br>as: Rasch-built Overall Disability Scale(R-ODS), modified INCAT sensory scale,<br /><br>Pain Intensity Rating scale, Rasch-Fatigue Severity Scale(FSS) and EuroQoL-5D<br /><br>questionnaire.</p><br>
- Secondary Outcome Measures
Name Time Method <p>nvt</p><br>