The effect of vitamin C on myocardial injury in coronary artery bypass surgery
Not Applicable
- Conditions
- coronary arthery heart disease.Atherosclerotic heart disease
- Registration Number
- IRCT2016053019470N33
- Lead Sponsor
- Vice Chancellor for Research, Shiaz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Patients undergoing CABG, completed consent form.
Exclusion criteria: history of preoperative arrhythmia; heart ejection fraction less than 30%; severe renal or hepatic failure; pacemaker, permanent or temporary, treatment with anti-arrhythmic drugs and digoxin; some degree of AV block or bradycardia with a heart rate less than 50 min; a history of recent myocardial infarction (less than one month); high initial troponin levels (> 0.3 macro gram per liter), re-operation (redo) or complex (valve replacement + CABG).
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the serum levels of CPK-MB, Troponin I, LDH. Timepoint: at the induction, termination of cardiopulmonary bypass, 6 hours after the procedure, 24 hours of operation. Method of measurement: Arterial blood samples.
- Secondary Outcome Measures
Name Time Method