The Impact of High Intensity Exercise Upon EPC Number and Function in Young Women
试验速览
- 阶段
- 不适用
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Maximal oxygen uptake
研究概览
简要总结
The purpose of the study is to examine the effects of different exercise intensity training programs upon blood vessel function and circulating blood cells involved in blood vessel repair in young women. The long term effects of exercise may be beneficial to cardiovascular health and it is important to understand the training methods that are the most beneficial. In particular we aim to determine if brief maximal exercise improves the function and stiffness of blood vessels and enhance blood vessel repair. Two methods of exercising are being compared, exercise bouts involving intermittent exercise and exercise completed all at once, but at a very high intensity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 25 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Young healthy females
- •Between 18-25 years old
- •No on medication (this includes contraceptives)
排除标准
- •Medication use (including oral contraceptives)
- •Amenorrhoea
- •High blood pressure
- •Very active (>3 hours per week of organized physical activity)
结局指标
主要结局
Maximal oxygen uptake
时间窗: 4 weeks
A measure of aerobic capacity determined during an incremental exercise test to volitional fatigue on an exercise ergometer.
次要结局
- Circulating angiogenic cell numbers(4 weeks)
- Heart rate variability(4 weeks)
- Arterial stiffness(4 weeks)
- Flow mediated dialtion(4 weeks)
- Endothelial progenitor cell function(4 weeks)