Development and Evaluation of Clinical efficacy of Novel Zinc oxide and Sodium Hyaluronate coated Stainless steel orthodontic archwire -Randomised control study.
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- 1. Rate of tooth movement
研究概览
简要总结
This study investigates the clinical efficacy of stainless steel orthodontic archwires coated with zinc oxide and sodium hyaluronate using physical vapor deposition. The research evaluates cytotoxicity, antimicrobial activity, surface properties, and frictional behavior of the coated wires. In vivo, the trial assesses rate of tooth movement, bacterial adhesion, periodontal health, and coating durability in patients undergoing fixed appliance therapy. Findings are expected to demonstrate reduced friction, improved antimicrobial resistance, and enhanced orthodontic outcomes compared to uncoated wires.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Day(s) 至 30.00 Year(s)（—）
- 性别
- All
入选标准
- •All 4 or upper 4 extraction cases ( upper 1 st premolar extraction cases)after end of levelling and aligning.
排除标准
- •Patient with systemic illness.
结局指标
主要结局
1. Rate of tooth movement
时间窗: 1. Rate of tooth movement- 3 months | 2. Bacterial adhesion-1 month
2. Bacterial adhesion
时间窗: 1. Rate of tooth movement- 3 months | 2. Bacterial adhesion-1 month
次要结局
- 1. coating wear and surface roughness of archwire(2.Notching of the archwire after retraction.)
研究者
Najiya VP
Saveetha Dental College, Chennai