Effect of intraoperative magnesium sulphate in craniotomy patients
Not Applicable
- Conditions
- Health Condition 1: G968- Other specified disorders of central nervous systemHealth Condition 2: G968- Other specified disorders of central nervous system
- Registration Number
- CTRI/2023/03/050300
- Lead Sponsor
- Dr Manoj Kumar Giri
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA Grade 1 and 2 patients
Elective craniotomies (both supratentorial and posterior fossa surgeries)
GCS 15
Exclusion Criteria
ASA Grade III and IV
Pregnant female
Patients with neuromuscular renal cardiovascular 0r hepatic insufficiency
BMI <18.5 or > 24.9kg/m2
Allergy to the study drugs
Those on treatment with calcium channel blockers or magnesium
Patients who will be shifted on ventilator post craniotomy
Anaesthesia time more than 5 hrs preventing excessive infusion of MgSO4
Any other mental or physical illness rendering them incapable of answering pain score
Patient on any previous chronic pain medications like gabapentin or pregabalin
Trauma and emergency craniotomies
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Effect of magnesium sulphate on reduction in post operative rescue analgesic requirement and post operative pain in the study groupTimepoint: start magnesium sulphate after induction till closure of dura.Post operative pain will be assessed at 1st hr 2nd hr 4th hr 6th hr 8th hr 12th hr 16th hr 20th hr and 24 hrs
- Secondary Outcome Measures
Name Time Method Effect of MgSO4 on reduction of intraop dose of Propofol and Vecuronium during surgeryTimepoint: start magnesium sulphate after induction till closure of dura