Influence of Anesthesia, Pneumoperitoneum, and Patient Position on Common Carotid Artery Blood Flow During Laparoscopic Gynecology Operation
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Perfusion
- Sponsor
- Seoul National University Hospital
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Change of the common carotid artery blood flow velocity
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
The investigators will evaluate the change of the common carotid artery blood flow according to patient's position and penumoperitoneum.
Detailed Description
The study will include 20 patients undergoing gynecological surgery. The common carotid artery blood flow will be measured using Doppler US during the following conditions; supine position before induction of anesthesia, supine position immediately after induction of anesthesia, supine position with penumoperitoneum, head-down position with or without pneumoperitoneum.
Investigators
Jin-Tae Kim
Professor
Seoul National University Hospital
Eligibility Criteria
Inclusion Criteria
- •ASA class I,II
- •patients undergoing gynecology surgery under trendelenburg position
- •Age ranges from 20 to 70
Exclusion Criteria
- •BMI \> 32
- •Pregnancy
- •Patients who did not agree to study
- •Patients with allergies to the drugs used in this study
- •Patients with anatomical variations or lesions in cervical or cranial vascular portion
- •Patients with arrhythmia that may alter patient's cardiac output(e.g. artrial fibrillation)
Outcomes
Primary Outcomes
Change of the common carotid artery blood flow velocity
Time Frame: 1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position
Common carotid artery blood flow velocity is measured using Doppler US
Secondary Outcomes
- Change of the common carotid artery beat volume(1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position)
- Change of the common carotid artery diameter(1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position)
- Change of mean arterial blood pressure(1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position)
- Change of cardiac output(1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position)
- Change of peak inspiration airway pressure(1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position)