Influence of Anesthesia, Pneumoperitoneum, and Patient Position on Common Carotid Artery Blood Flow During Laparoscopic Gynecology Operation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Change of the common carotid artery blood flow velocity
研究概览
简要总结
The investigators will evaluate the change of the common carotid artery blood flow according to patient's position and penumoperitoneum.
详细描述
The study will include 20 patients undergoing gynecological surgery. The common carotid artery blood flow will be measured using Doppler US during the following conditions; supine position before induction of anesthesia, supine position immediately after induction of anesthesia, supine position with penumoperitoneum, head-down position with or without pneumoperitoneum.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •ASA class I,II
- •patients undergoing gynecology surgery under trendelenburg position
- •Age ranges from 20 to 70
排除标准
- •BMI > 32
- •Pregnancy
- •Patients who did not agree to study
- •Patients with allergies to the drugs used in this study
- •Patients with anatomical variations or lesions in cervical or cranial vascular portion
- •Patients with arrhythmia that may alter patient's cardiac output(e.g. artrial fibrillation)
结局指标
主要结局
Change of the common carotid artery blood flow velocity
时间窗: 1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position
Common carotid artery blood flow velocity is measured using Doppler US
次要结局
- Change of the common carotid artery beat volume(1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position)
- Change of the common carotid artery diameter(1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position)
- Change of mean arterial blood pressure(1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position)
- Change of cardiac output(1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position)
- Change of peak inspiration airway pressure(1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position)
研究者
Jin-Tae Kim
Professor
Seoul National University Hospital