Internal Carotid Artery Blood Flow in Infants With Prone Position
- Conditions
- Cerebral Lesion
- Registration Number
- NCT05391282
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
Little is known about how implementation of prone position contributes to general anesthesia-induced decrease in cerebral blood flow in infants. The investigators investigated this question in participants undergoing untethering, hypothesizing that cardiorespiratory changes during this procedure would reduce cerebral perfusion.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- pediatric neurosurgical patients receiving surgery under prone position
Exclusion Criteria
- patients diagnosed as hydrocephalus
- premature closure of fontanelle
- patients diagnosed as patent ductus arteriosus or other congenital heart disease.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes of internal carotid artery blood flow velocity from induction of anesthesia to end of operation, about 3 hours
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link prone positioning to cerebral blood flow changes in infants under anesthesia?
How does transfontanel ultrasound compare to other imaging techniques for monitoring carotid artery flow in neonates?
Are there specific biomarkers that correlate with cerebral perfusion reduction during prone positioning in pediatric patients?
What are the potential adverse effects of prolonged prone positioning on cerebral hemodynamics in infants with cerebral lesions?
How do cardiorespiratory changes in the Trendelenberg position affect cerebral oxygenation in neonatal populations?
Trial Locations
- Locations (1)
Seoul national university hospital
🇰🇷Seoul, Korea, Republic of
Seoul national university hospital🇰🇷Seoul, Korea, Republic of