Comparing the effectiveness of saline irrigation and Bactisure® solution in debridement surgery for acute periprosthetic joint infections
- Conditions
- Patients diagnosed with acute or hematogenous periprosthetic hip or knee infection (PJI) eligible for debridement, antibiotic and implant retention (DAIR) surgerySurgery
- Registration Number
- ISRCTN10873696
- Lead Sponsor
- Vall d'Hebron Institut de Recerca
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- All
- Target Recruitment
- 50
1. Age >18 years old
2. Patients with hip or knee prostheses
3. Diagnosis of periprosthetic joint infection according to the criteria established in the Second International Consensus on Musculoskeletal Infections
4. Acute PJI: <6 weeks since the initial arthroplasty surgery
5. Acute hematogenous PJI: <3 weeks from symptom onset, documented bacteremia (positive blood culture) with the same microorganism in joint fluid
6. No previous debridement surgeries
7. Surgery performed: DAIR
1. Patients who do not voluntarily and without coercion agree to participate in this clinical trial
2. Patients under 18 years of age
3. Prosthetic reinfections or a history of multiple debridements
4. Known sensitivity or allergic reaction to ethanol, acetic acid, sodium acetate, or benzalkonium chloride
5. Diagnosis of Chronic PJI: the presence of fistula or >6 weeks
6. Multiple infected implants (>1)
7. Medically unfit for DAIR surgery
8. Pregnancy
9. Legal incapacity
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method