The Tranexaminic acid - Aprotinin - Placebo trial.

Completed

• Conditions: Intra-operative medication trial.

• Registration Number: NL-OMON25344
• Lead Sponsor: /A

Brief Summary

/A

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 300

Inclusion Criteria

Patients scheduled for first time, non-complex (one or two procedures) open heart surgery with the use of CPB.

Exclusion Criteria

1. Less than 18 years old;

2. Previous sternotomy;

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Intraoperative and perioperative blood loss;<br /><br>2. Intraoperative and perioperative use of blood products.

Secondary Outcome Measures

Name	Time	Method
1. Rethoracotomies;<br /><br>2. The total duration of each patient's stay in the operating room;<br /><br>3. Length of stay in the ICU and hospital;<br /><br>4. Development of SIRS/sepsis/MOF;<br /><br>5. 30-day morbidity;<br /><br>6. 30-day mortality;<br /><br>7. Costs.