ung protective mechanical ventilation versus regular mechanical ventilation in patients undergoing vascular surgery of the lower limbs.
Not Applicable
- Conditions
- ung DiseasesC08.381
- Registration Number
- RBR-5stpwb
- Lead Sponsor
- Hospital de Clinicas de Porto Alegre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruitment completed
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Adult ASA II to IV patients; older than 18 years; scheduled to undergo arterial bypass surgery in the lower limbs.
Exclusion Criteria
Patients with a body mass index above 40 kg / m2; submitted to emergency surgery; with a history of pulmonary surgery; persistent hemodynamic instability in the preoperative period; history of asthma or chronic use of corticosteroids; or patients with a history of neuromuscular disorder.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluate the effects of mechanical ventilation with a protective strategy (treatment group - low tidal volume and high PEEP) in comparison to conventional mechanical ventilation (control group - high tidal volume and reduced PEEP) on the incidence of pulmonary complications (primary composite endpoint: insufficiency pulmonary infiltrates, pleural effusions, bronchospasm, cardiopulmonary edema, acute respiratory distress syndrome (ARDS)) in the perioperative period of patients undergoing coronary artery bypass graft surgery (CABG). Measures performed by clinical, laboratory or radiological means.<br><br>
- Secondary Outcome Measures
Name Time Method