Evaluation of a protective ventilation strategy in patients undergoing major neurosurgery: a pilot study

Not Applicable

Completed

• Conditions: Protective mechanical ventilation strategy; Anaesthesiology - Other anaesthesiology

• Registration Number: ACTRN12615000707561
• Lead Sponsor: Federico Longhini, MD

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-07-08
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

All the patients meeting the following criteria will be eligible for the study: 1) age equal or greater than 18 years; 2) cerebral or spinal neurosurgery with an expected duration equal or greater than 4 hours, 3) risk index for pulmonary post-operative complications greater than 2; 4) no need for post-operative ICU.

Exclusion Criteria

Patients will be excluded if meeting one or more of the following criteria: 1) mechanical ventilation in the previous 2 weeks 2) BMI equal or greater than 35 3) sepsis or acute rspiratory failure in the previous 2 weeks 4) emergent or urgent surgery 5) neuromuscular diseases 6) consent withdraw.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate if a protective ventilation strategy is safety (i.e. number of intraoperative complications like desaturation or hypotension) during a major neurosurgery [Immediately at the completion of the surgery];To evaluate if a protective ventilation strategy is feasible (i.e. evaluation of the cerebral tension by the surgeon, possibility of optimal control of arterial carbon dioxide) during a major neurosurgery.[Immediately at the completion of the surgery]