The bacteria associated with periodontal disease before and after treatment.

Not Applicable

Completed

• Conditions: Periodontitis; Infection - Studies of infection and infectious agents; Inflammatory and Immune System - Other inflammatory or immune system disorders; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

• Registration Number: ACTRN12619001307190
• Lead Sponsor: Samantha Byrne

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2019-02-15
• Study Start: 2019-09-25
• Last Update Posted: 7 October 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

Patients with periodontitis as determined by the presence of at least 4 diseases single-rooted teeth defined by >/= 1 site a the tooth with a probing pocket depth of >/= 5 mm with bleeding on probing.

Exclusion Criteria

Use of antibiotics in the prior 3 months, pregnancy or lactation, systemic conditions which may affect the progression of periodontitis (eg diabetes), any condition requiring premedication prior to treatment, long-term therapy with non-steroidal anti-inflammatory drugs and history of periodontal treatment within the past 3 months.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Periodontal pocket depth. Periodontal pocket depth will be measured to the nearest millimeter manually using a graduated periodontal probe. [Three months after completion of non-surgical periodontal treatment. ]

Secondary Outcome Measures

Name	Time	Method
Bleeding on probing. This will be recorded visually as either present or absent by the clinician immediately after recording the periodontal pocket depth. [3 months following completion of the non-surgical periodontal treatment, at the same appointment as the periodontal pocket depth is recorded. ];Microbial community profile of subgingival plaque.[The subgingival plaque will be collected 3 months post non-surgical therapy. Laboratory analysis of these samples will take 8 - 12 weeks for results.]