Comparison of the effect of memantine on NSE and GCS among traumatic brain injury patients
Not Applicable
- Conditions
- Traumatic brain injury.Intracranial injury
- Registration Number
- IRCT20100107003014N25
- Lead Sponsor
- Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Traumatic brain injury (TBI)
Glasgow Coma Scale (GCS) between 6-12
Being at the age of 18 years old and above
The patient can tolerate the drug in the first 24 hours after traumatic brain injury
Exclusion Criteria
Diabetes mellitus, uncontrolled (random blood sugar greater than 200 mg / dL at the time of administration)
Acute myocardial infarction in the last 48 hours
Acute or chronic renal failure, creatinine clearance less than 60 ml per minute
Autoimmune disorders and malignant diseases
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method euron-specific enzyme (NSE). Timepoint: Days 1, 3 and 7. Method of measurement: Laboratory test.;Glasgow coma scale. Timepoint: Days 1, 3 and 7. Method of measurement: clinical.
- Secondary Outcome Measures
Name Time Method Survival / Death. Timepoint: 3 months later. Method of measurement: Phone call with patient.