Correlation of mitral annular plane systolic excursion with left ventricular Ejection Fraction and Global Longitudinal Strain in patients with varying degrees of left ventricular systolic dysfunction.

Study will be conducted in the Department of Cardiology, Kasturba Hospital, Manipal. Patients who are diagnosed with left ventricular systolic dysfunction(new onset/previously diagnosed) and who fulfill the inclusion criteria will be included. Informed consent will be taken from the patients in the language they understand best and

those willing to participate in the study after fully understanding the nature of the study and risks/benefits will be included.This is an observational, cross sectional study, in which standard echocardiographic evaluation would be done,under ECG gating, as a part of standard care of the patients with LV systolic dysfunction. Standard echocardiographic measurements will be obtained in accordance with the current guidelines of the American Society of Echocardiography/European Association of Cardiovascular Imaging.Primary outcome measured in this study will be MAPSE and its correlation with LV systolic dysfunction and EF and global longitudinal strain.Secondary outcomes will include its correlation with degree and severity of LV dysfunction, and its correlation with diastolic dysfunction.MAPSE can be used as an early and sensitive marker of LV systolic dysfunction, especially to identify such patients early. Potential risks in this study are minimal as study requires only extra parameters that will be studied in the ECHO.