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Clinical Trials/NCT04817267
NCT04817267
Terminated
Not Applicable

Pilot Study of reSET-O to Treatment-as-usual in Acute Care Settings

Johns Hopkins University1 site in 1 country8 target enrollmentMarch 11, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Opioid-use Disorder
Sponsor
Johns Hopkins University
Enrollment
8
Locations
1
Primary Endpoint
Acceptability as assessed by the System Usability Scale
Status
Terminated
Last Updated
last year

Overview

Brief Summary

This randomized controlled pilot study will evaluate feasibility, acceptability, and potential efficacy of an app, reSET-O, for patients being started on buprenorphine in acute care settings.

Detailed Description

This randomized controlled pilot study will enroll 60 participants, who will be randomly assigned to a treatment as usual (TAU) group or a reSET-O+TAU group after being started on buprenorphine in acute care settings (e.g., emergency department) and referred to community treatment. Study enrollment will last for 3 months after discharge from the acute care setting. Participants in the reSET-O+TAU group will be provided with the reSET-O app and will be encouraged to engage with the app for the 3 months following discharge from the acute care unit. The app works as an extension of cognitive behavioral therapy, providing psychoeducation related to opioid use disorder. All participants will be assessed at study intake and every month during the 3-month intervention.

Registry
clinicaltrials.gov
Start Date
March 11, 2022
End Date
May 1, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • 18-65 years old
  • Opioid use disorder
  • Eligible for buprenorphine treatment
  • Has reSET-O compatible mobile device

Exclusion Criteria

  • Pregnancy
  • Significant psychiatric comorbidity

Outcomes

Primary Outcomes

Acceptability as assessed by the System Usability Scale

Time Frame: 3 months

Participant responses to the System Usability Scale.

Percentage of approached patients who are eligible for and interested in participation

Time Frame: 3 months

Percentage of approached patients who are eligible for and interested in participation will be used to assess feasibility.

Acceptability as assessed by the Treatment Acceptability Questionnaire

Time Frame: 3 months

Participant responses to the Treatment Acceptability Questionnaire.

Secondary Outcomes

  • Percentage of drug-negative urine samples during the 3-month intervention(3 months)
  • Attendance at follow-up appointment for on-going buprenorphine treatment within 30 days of discharge(30 days)

Study Sites (1)

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