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Efficacy and Safety of BGG492 in the Treatment of Migraine

Phase 2
Completed
Conditions
Migraine
Interventions
Drug: BGG492
Drug: Sumatriptan
Drug: Placebo
Registration Number
NCT00892203
Lead Sponsor
Novartis
Brief Summary

This study will assess the efficacy and safety of BGG492 used to treat migraine pain.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
75
Inclusion Criteria
  • Diagnosis of moderate to severe migraine for at least 1 year
  • At least 1 migraine episode, but not more 15 migraine days per month
  • Past use of triptans
  • Migraine onset before 50 years of age
Read More
Exclusion Criteria
  • Diagnosis of basilar, ophthalmoplegic or hemiplegic migraine.
  • More than 6 non-migraine headaches per month
  • Patients receiving migraine prophylaxis treatment
  • Patients receiving regular treatment with psychoactive drugs
  • Smokers
  • Patients with a very high or low body weight Other protocol-defined inclusion/exclusion criteria may apply
Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
ActiveBGG492-
ComparatorSumatriptan-
PlaceboPlacebo-
Primary Outcome Measures
NameTimeMethod
Reduction in migraine pain2 hours
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (4)

California Clinical Trials, 1560 Chevy Chase Drive, Suite 140

🇺🇸

Glendale, California, United States

California Clinical Trials, 15625 Lakewood Boulevard

🇺🇸

Paramount, California, United States

Novartis Investigator Site

🇩🇪

Munich, Germany

Novartis Investigative Site

🇪🇸

Barcelona, Spain

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