Role of cerebral blood flow pulsatility in hypertension related brain damage - HYBRiD-Flow

Medisch Universitair Ziekenhuis Maastricht0 个研究点目标入组 50 人开始时间: 待定最近更新: 2024年6月11日

适应症

试验速览

暂无简介。

•Patients with essential hypertension (HTN):
•- Indication of history-taking, physical examination or routine laboratory
•tests of secondary
•hypertension
•- Chronic renal insufficiency (eGFR<30 mL/min)
•- Diabetes mellitus
•- Ischemic or valvular heart disease or electrocardiographic evidence of atrial
•fibrillation
•- Carotid endarterectomy (CEA): high-grade stenosis > 50%
•- Hemorrhagic stroke
•- Body Mass Index > 32 kg/m²
•- Inability to provide informed consent
•- Any contraindication for MRI: metallic implants, pacemaker, claustrophobia,
•pregnancy, tattoos,
•permanent make-up.
•- Contraindications for the gadolinium-containing contrast agent: allergic
•reaction, eGFR<30
•Normotensive subjects (NT):
•- Indication of history-taking, physical examination or routine laboratory
•tests of secondary
•hypertension
•- Chronic renal insufficiency (eGFR<30 mL/min)
•- Diabetes mellitus
•- Ischemic or valvular heart disease or electrocardiographic evidence of atrial
•fibrillation
•- Carotid endarterectomy (CEA): high-grade stenosis > 50%
•- Hemorrhagic stroke
•- Body Mass Index > 32 kg/m²
•- Inability to provide informed consent
•- Any contraindication for MRI: metallic implants, pacemaker, claustrophobia,
•pregnancy, tattoos,
•permanent make-up.
•- Contraindications for the gadolinium-containing contrast agent: allergic
•reaction, eGFR<30

发起方

Medisch Universitair Ziekenhuis Maastricht