Airway Clearance by Fiberoptic Bronchoscopy in Bronchiectasis Followed by Gentamicin and Dexamethason Injection

Not Applicable

Completed

• Conditions: Bronchiectasis Adult; Bronchiectasis with Acute Exacerbation

• Registration Number: NCT06906354
• Lead Sponsor: Alexandria University

Brief Summary

Fiberoptic Bronchoscopic Removal of Secretions and Antibiotic Injection

Detailed Description

fiberoptic bronchoscopic injection of dexamethason and gentamicin after airway clearance

Study Timeline

• Study Start: 2024-11-11
• Status Verified: 2025-01
• Primary Completion: 2025-01-15
• Study Completion: 2025-01-20
• Study First Submitted: 2025-03-26
• Study First Submitted QC: 2025-03-26
• Last Update Submitted: 2025-03-26
• Study First Posted: 2025-04-02
• Last Update Posted: 2025-04-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1- Adult subjects. 2- Male and female subjects are enrolled. 3- patients with NCFB confirmed by chest high-resolution computed tomography (HRCT) 4- patients needing antibiotic treatment at the hospital due to exacerbation 5- Patients who underwent AC by bronchoscopy at the hospital.

Exclusion Criteria

1- Uncooperative subjects. 2- Unwilling to participate. 3- Inability to lie on the back with raised arms over the head for HRCT. 4- Presence of cystic pulmonary fibrosis; 5- Patients with active pulmonary tuberculosis; 6- Those awaiting surgery; 7- Patients who underwent interventional therapy for hemoptysis; those with allergic bronchopulmonary aspergillosis (ABPA); 8- Patients who did not undergo bronchoscopy for different reasons or combined with lung cancer.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Dyspnea Borg Scale	one month	improvement in the scale of dyspnea before and after the procedure

Trial Locations

Locations (1)

Chest Department -Faculty of Medicine; 🇪🇬 Alexandria, Egypt