Comparison of the Hemodynamic parameters of two regimens propofol-ketamin & etomidate during anesthesia induction in low EF CABG patients
Phase 2
- Conditions
- Hemodynamic Change.Postprocedural disorder of circulatory system, unspecified
- Registration Number
- IRCT201207184365N14
- Lead Sponsor
- Vice chancellor for research of Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
First time elective CABG surgery; Age between 40 and 70 years; EF<40%
Exclusion criteria:70 >MAP>110 mmHg; CABG with valve operation; Received etomidate or propofol or thiopental in one week ago; Egg and soy allergy; Sensitivity to etomidate or propofol or ketamine; Adrenal insufficiency
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean arterial pressure. Timepoint: Before laryngoscopy as well as immediately, 1, 2 and 3 min after tracheal intubation. Method of measurement: Invasive Blood Pressure.;Systolic blood pressure. Timepoint: Before laryngoscopy as well as immediately, 1, 2 and 3 min after tracheal intubation. Method of measurement: Invasive Blood Pressure.;Diastolic blood pressure. Timepoint: Before laryngoscopy as well as immediately, 1, 2 and 3 min after tracheal intubation. Method of measurement: Invasive Blood Pressure.;Heart rate. Timepoint: Before laryngoscopy as well as immediately, 1, 2 and 3 min after tracheal intubation. Method of measurement: Heart monitoring.
- Secondary Outcome Measures
Name Time Method Muscle twitching. Timepoint: After anesthetic infusion. Method of measurement: Inspection.;Pain on injection. Timepoint: After anesthetic infusion. Method of measurement: Inspection.