Therapeutic Effect of Using Injectable Hypertonic Saline 5% Versus Injectable Dextrose 20% on Pain in Painful Cases of Disc Displacement with Reduction ( a Randomized Clinical Trial)
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 20
- 主要终点
- Severity of pain
研究概览
简要总结
This study is aiming to assess effect of hypertonic saline 5% in comparison to dextrose 20% on pain ,inter-insical opening and movements of jaw in painful cases of disc displacement with reduction
详细描述
Intra-articular disorders of the TMJ have been defined as an abnormal positional relationship between the disc and the condyle, articular eminence, and/or articular fossa.
The term internal derangement of the temporomandibular joint (TMJ) indicates an abnormal relationship between the disc, the condyle, and the articular eminence that constrains proper joint function
The disc displacement could be with or without reduction. In disc displacement with reduction, the disc is displaced anterior to the condylar head and remains in this position as long as the mouth is closed. Upon mouth opening, the disc regains its position on the condylar head. The movement of the disc onto and off the condylar head may lead to a clicking sound .
The precise source of internal derangements is not clear; however, it is a complex disorder likely caused by a combination of micro- or macro-trauma, parafunctional behavior, laxity of the joint's soft tissues, and alterations in the synovial fluid's composition
The aims of the internal derangement treatment include alleviating pain, reducing or eliminating joint noises, increasing the degree of mouth opening, and consequently restoring normal TMJ function.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Care Provider)
入排标准
- 年龄范围
- 15 Years 至 75 Years(Child, Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •presence of one or more of the following observations in one or both temporomandibular joints:
- •audible clicking.
- •mandibular deviation on opening.
- •Failure of conservative treatment
排除标准
- •The clinical or radiographic signs of disc displacement without reduction, osteoarthritis, or articular bony changes.
- •Previous TMJ surgery, arthrocentesis, , or the presence of any systemic disease that would affect the TMJ anatomy or mechanical function.
- •A history of allergic reactions to any components of the injectable solution.
- •Infection of the affected joint and pre-auricular area.
- •Previous surgery of the affected joint
研究组 & 干预措施
painful cases with disc displacement with reduction
painful cases of disc displacement with reduction
干预措施: hypertonic saline 5% sodium chloride (Other)
结局指标
主要结局
Severity of pain
时间窗: baseline and at 6 months
severity of pain is measured by Visual analog scale (VAS) From (0-10) Where 0: no pain 10: worst pain
次要结局
未报告次要终点
研究者
Aya Allah Gamal Salah
Aya Allah Gamal
Cairo University
