A Study of Cardiac Phenotypes in Sepsis
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 112
- Locations
- 1
- Primary Endpoint
- To determine the prevalence of various cardiac manifestations in patients diagnosed as sepsis in order to understand specific treatment provided depending on cardiac outcomes.
Study Overview
Brief Summary
The proposed study involves obtaining ethical clearance and informed consent before conducting a prospective, longitudinal investigation into sepsis among ICU patients. It will recruit patients diagnosed with sepsis using the SOFA score, focusing on those admitted under general medicine. Data collection will include medical history, laboratory results, and clinical assessments. Echocardiography within 24 hours of admission will evaluate cardiac function, with particular attention to indicators of distributive or hypodynamic shock. RV dysfunction will be assessed using TAPSE, and the IVC diameter will be measured. Patient safety and confidentiality will be paramount throughout the study. Follow-up will continue for 28 days post-admission to monitor patient outcomes.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18.00 Year(s) to 99.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Patients diagnosed to have sepsis by sepsis 3 guidelines and seeking treatment for the same at kasturba Medical College under General Medicine Department.
Exclusion Criteria
- •Pre-existing Valvular Heart Disease/ Pre-existing Congenital Heart Disease/ Pregnancy/ Atrial Fibrillation/Cardiac arrest within 48 hours of presentation/ Ascites/ Pneumothorax.
Outcomes
Primary Outcomes
To determine the prevalence of various cardiac manifestations in patients diagnosed as sepsis in order to understand specific treatment provided depending on cardiac outcomes.
Time Frame: 24 hours,28 days
Secondary Outcomes
- To draw comparison between various cardiac phenotypes through deranged(clinical parameters,prognosis and mortality rates.)
Investigators
Rajika Khanna
Kasturba Medical College Manipal