ACTRN12615001176550招募中未知
In participants with Conversion disorder and healthy volunteers, does a short term intervention with a breathing stress reduction technique followed by up to 2 years of psychotherapy with the Conversational model lead to improved processing of stress, as evidenced by psychological questionnaires, heart rate variability and attachment status.
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 130
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Treatment
入排标准
- 年龄范围
- 18 Years 至 65 Years（—）
- 性别
- All
入选标准
- •English speaking
- •1. A diagnosis of conversion disorder, psychogenic faints or somatization disorder with conversion symptom/s, all with or without somatoform pain. DSM-V criteria will be used for recruitment with all cases co-classified on DSM-IV. This is to facilitate comparison with earlier child study which utilised DSM-IV.
- •Cases may present with a range of neurological symptoms including motor disturbance/impairment; sensory
- •impairment, cognitive impairment, psychogenic non-epileptic seizures (PNES) or faints, and with or without somatoform pain.
- •2. Must have undergone neurology assessment through the Neurology service at Westmead hospital to establish or verify the diagnosis of conversion disorder and to exclude other medical causes for the presenting symptoms/syndromes prior to taking part in the current research.
- •Healthy/normative adults.
排除标准
- •General Exclusion Criteria
- •1. Insufficiently fluent in English to complete processes of consent and study protocol;
- •2. Developmental disability;
- •3. Adults who have a family history of genetic disorders;
- •4. Chronic medical illness including any impediment to vision, hearing, or hand
- •movement that prevents completion of the study protocol;
- •5. Adults with a history of brain injury, or head injury that resulted in unconsciousness within the last 5 years. This is due to the risk of later neurological sequelae such as seizures which may not yet be evident but could impact cognitive and psychological parameters.
- •6. Adults who, in the opinion of the investigator/s, are unable or unlikely to comprehend or follow the study procedures and instructions due to distress or some other difficulty with language, comprehension or cognition.
- •7. Adults with co-morbid severe substance use disorder. This is because substances can influence autonomic nervous system reactivity and make it difficult to determine whether a recorded effect is due to the substance use disorder or the conversion disorder.
- •Group A Specific Exclusion Criteria:
- •Exclusion criteria include those listed in DSM-V for conversion disorder including another medical explanation for symptoms, such as symptoms limited to fatigue, or a substance use disorder, for reasons described above.
- •Specifically, patients with other co-morbid psychiatric illnesses are not excluded. This is because patients with conversion disorder have a large array of co-morbid psychiatric diagnoses. Excluding those patients with other psychiatric illnesses would therefore lead to a non-representative sample of typical patients presenting to tertiary assessment centres, making the sample biased.
- •Group B Specific Exclusion Criteria
- •Adults with a previous or current Axis-I or Axis II DSM-IV-R diagnosis will be excluded. We understand that this is a stringent requirement where community mental
- •health diagnoses are not uncommon but, for the clarity of the groups, is necessary.
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