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Comparative Analysis of Esmolol and Dexmedetomidine for Optimal Surgical Field Conditions in Functional Endoscopic Sinus Surgeries: A Prospective Randomized Clinical Study

Phase 2
Conditions
Health Condition 1: J324- Chronic pansinusitis
Registration Number
CTRI/2024/01/061084
Lead Sponsor
JLN Medical College Ajmer
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

body weight 40kg to 70kg,

ASA grade I or II,

scheduled for surgery under General Anaesthesia

Exclusion Criteria

patient not willing to participate in the study uncooperative patient,

patients with a history of drug allergies,

patients with pre-existing disease like asthma, hepatic or renal dysfunction,

pregnant or lactating,

morbidly obese patient

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Haemodynamic parameters like heart rate, systolic blood pressure, <br/ ><br>diastolic blood pressure and mean arterial blood pressure from baseline at different time intervals <br/ ><br>in both groups that is, group receiving esmolol and the group receiving dexmedetomidine during Functional Endoscopic Sinus Surgeries.Timepoint: 1 year and 6 months
Secondary Outcome Measures
NameTimeMethod
Emergence time, sedation score, VRS scale score in post-operative field and time to first rescue analgesic after surgeryTimepoint: 1 year and 6 months;Proportion of cases with complications.Timepoint: 1 year and 6 months;Quality of intra-operative surgical field by using average categorical scale in both groups.Timepoint: 1 year and 6 months
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