Comparison of analgesic effect of ropivacaine with dexmedetomidine and ropivacaine with clonidine in lower limb orthopaedic surgeries

Phase 4

Not yet recruiting

• Conditions: Measurement and Monitoring, (2) ICD-10 Condition: O||Medical and Surgical,

• Registration Number: CTRI/2023/03/050845
• Lead Sponsor: Aarupadai veedu medical college and hospital

Brief Summary

Aim of my study is to assess and evaluate the analgesic effect of dexmedetomidine and clonidine added to 0.75% hyperbaric ropivacaine in spinal anesthesia in lower limb orthopedic surgeries with onset of anesthesia, duration of analgesia and hemodynamic changes

Primary objective :- to compare the duration of post-operative analgesia by intrathecal administration of 0.75% hyperbaric ropivacaine with dexmedetomidine versus clonidine.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-03-18
• Study Start: 2023-03-28

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• Patients with 18-60 years ASA I and ASA II Weight.
• 50-80 kgs Orthopaedic lower limb cases.

Exclusion Criteria

ASA III and more Hypersensitivity to any drugs used in study Uncontrolled diabetic mellitus and hypertension Cardiac dysrhythmias Coagulopathies.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare post-operative analgesia of dexmedetomidine versus clonidine as adjuvant added to hyperbaric ropivacaine	To compare post-operative dexmedetomidine versus Clonidine as adjuvant added to hyperbaric ropivacaine

Secondary Outcome Measures

Name	Time	Method
Motor blockade	Sensory blockade

Trial Locations

Locations (1)

Aarupadai veedu medical college and hospital; 🇮🇳 Pondicherry, PONDICHERRY, India

Aarupadai veedu medical college and hospital

🇮🇳Pondicherry, PONDICHERRY, India

Darpally Priyanka

Principal investigator

8008109933

priyankadaripally@gmail.com