The acute effects of Yohimbine on fear conditioning and the neural processing of emotional images, and on delayed extinction learning and memory for the images.
Phase 4
- Conditions
- Healthy subjects, investigating the mechanisms underpinning Post Traumatic Stress DisorderMental Health - Studies of normal psychology, cognitive function and behaviour
- Registration Number
- ACTRN12611000820909
- Lead Sponsor
- niversity of New South Wales
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Healthy University Students.
Right handed.
Exclusion Criteria
Current course of medication (including hormonal contraceptive for female participants), pregnancy or breasfeeding, substance abuse / dependence, current or recent history of psychiatric conditions, current or recent medical conditions, suicidal thoughts, known sensitivity to Hydrocortisone or Yohimbine, post-menopausal (for female participants), any participants with metal implants in the body. Participants are instructed not to drink alcohol or take any illegal drugs on the day of drug administration, and to abstain from fluids and food for two hours prior to drug administration.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method