Favorable / suitable amount of injection Ephedrine to be given as a precaution to avoid lowering of blood pressure soon after spinal anaesthesia during caesarean secton in pregnant patients
Phase 3
Completed
- Conditions
- Health Condition 1: O82- Encounter for cesarean delivery without indication
- Registration Number
- CTRI/2019/10/021524
- Lead Sponsor
- Dr BIMAL KRUSHNA PANDA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
All patients 18-45 years, scheduled for LSCS procedures under spinal anaesthesia belonging to ASA Grade I and Grade II will be included in the study.
Exclusion Criteria
1. Parturients with gestational age <37 weeks
2. High risk pregnancy
3. Known Hypertension
4. Preexisting cardiac or pulmonary disease
5. Any other contraindication of spinal anaesthesia
6. ASA physical status III and IV
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 7.5 mg of injection Ephedrine will be a more effective optimal intravenous prophylactic dose than other bolus doses and equal volume of normal saline that is to be administered to LSCS patients soon after spinal anaesthesia to avoid spinal induced hypotension.Timepoint: 1 <br/ ><br>Incidence of hypotension
- Secondary Outcome Measures
Name Time Method 1. 7.5mg of IV Ephedrine will bring a better haemodynamic stability. There will be no significant differences in baseline HR and systolic BP with 7.5mg iv bolus ephedrine in comparison to other study groups. <br/ ><br>2. There will be no significant differences in sensory block height with 7.5mg iv bolus ephedrine <br/ ><br>3. The incidence of nausea and vomiting and statistical differences of neonatal outcome at 1min and 5min Apgar scores will be lower with 7.5mg IV ephedrineTimepoint: 5 <br/ ><br>Heart rate and Blood pressure <br/ ><br>Sensory block height <br/ ><br>Apgar score <br/ ><br>Incidence of nausea <br/ ><br>Incidence of vomiting