Better Identification of Latent Tuberculosis Infection Among Israeli Young Adults by Comparison Skin Tests and Interferon Gamma Releasing Assays (IGRA)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 115
- 试验地点
- 3
- 主要终点
- Interferon gamma release assay ( IGRA)
研究概览
简要总结
The aim of study is to evaluate the prevalence of latent TB in second generation immigrants from countries with high incidence of tuberculosis (above 20 of 100,000) compare to the control native Israelis without a family member who was born in a country with high incidence of tuberculosis. Using study questionnaire IGRA and tuberculin skin test the investigators expect that the second generation immigrants group will have more positive IGRA test than the control native group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 25 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 18-25
- •Men and women
- •Second generation immigrants from countries with high incidence of tuberculosis (above 20 of 100,000).
- •Native Israelis without a family member who was born in a country with high incidence of tuberculosis.
排除标准
- •Prior contact with a tuberculosis patient
- •Working (more than a month) in high risk setting such as health care workers, working with immigrants from countries with high incidence of tuberculosis.
- •HIV infection and any immunodeficiency condition.
- •Recent live-virus vaccination
- •Acute infectious disease
- •Prior serious reaction to tuberculin skin test
- •Pregnancy
研究组 & 干预措施
Second generation immigrants from high TB incidence countries
Answering the study Questionnaire and blood sampling for Interferon gamma release assay (IGRA).
干预措施: Answering the study Questionnaire and blood sampling for Interferon gamma release assay (IGRA) (Procedure)
Native Israelis
Answering the study Questionnaire and blood sampling for Interferon gamma release assay (IGRA).
干预措施: Answering the study Questionnaire and blood sampling for Interferon gamma release assay (IGRA) (Procedure)
结局指标
主要结局
Interferon gamma release assay ( IGRA)
时间窗: Up to 3 months after tuberculin skin test
次要结局
未报告次要终点