Construction of Modern reGional Network for Acute Myocardial Infarction
试验速览
- 阶段
- 不适用
- 入组人数
- 7,102
- 试验地点
- 8
- 主要终点
- Receipt of reperfusion therapy within 12 hoursInfarction patients
研究概览
简要总结
Incidence of ST-segment Elevation Myocardial Infarction (STEMI) is rising and the existing emergency medical aid system for STEMI was not enough for timely perfusion treatment. No existing research with high-quality data focuses on the characteristic of STEMI incidence and regional network construction. Aiming of Guangdong GAMI(reGional network for Acute Myocardial Infarction) project is to establish effective collaborative regional network system for STEMI patients treatment.
详细描述
The project of Guangdong GAMI(reGional network for Acute Myocardial Infarction) is being conducted during 2015-2019 in eight districts with diverse economic development across southern China (Integrated care model was conducted in four regions, which mainly included community public education, non primary-PCI capable centre and referral system improvement, and inhospital green-channal optimization for primary-PCI capable centre. Other four centers were underwent usual care of acute myocardial infacrtion public and medical health service). All the ST-segment elevation myocardial infarction (STEMI) patients admitted in the hospital within 30 days from the symptom onset were enrolled. The key data of the timeline of STEMI onset and treatment were precisely recorded. Other details of STEMI treatment in hospitals such as laboratory data and medication were also collected. During the research period, actions of both optimizing the regional STEMI patients transfer and treatment to shorten the medical delay, as well as educating the public to improve their awareness of early treatment of STEMI were taken meanwhile. In addition, laboratory data, medication, and follow-up information were recorded in a database for further analysis regarding the STEMI patient treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Sequential
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All adult patients who suspected diagnosis with STEMI.
排除标准
- •patients refused to undergo coronary angiography;
- •patients were confirmed as non-STEMI by coronary angiography or the course of STEMI over 1 month;
- •patients occurred onset STEMI during hospitalization in hospitals
结局指标
主要结局
Receipt of reperfusion therapy within 12 hoursInfarction patients
时间窗: From 1 month before hospitalization to 24 hours after hospitalization
The primary outcome was the proportion of patients who received symptom-to-reperfusion treatment within 12 hours.
次要结局
- In-hospital clinical outcomes(30 days)
- 1-year all-cause mortality(1 year)
- Onset-to-admission time within 12 hours(From 1 month before hospitalization to 24 hours after hospitalization)
- Door-to-balloon time within 90 minutes(24 hours)
研究者
Jiyan Chen
Professor
Guangdong Provincial People's Hospital