Construction of Modern reGional Network for Acute Myocardial Infarction
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Coronary Heart Disease
- Sponsor
- Guangdong Provincial People's Hospital
- Enrollment
- 7102
- Locations
- 8
- Primary Endpoint
- Receipt of reperfusion therapy within 12 hoursInfarction patients
- Last Updated
- 3 years ago
Overview
Brief Summary
Incidence of ST-segment Elevation Myocardial Infarction (STEMI) is rising and the existing emergency medical aid system for STEMI was not enough for timely perfusion treatment. No existing research with high-quality data focuses on the characteristic of STEMI incidence and regional network construction. Aiming of Guangdong GAMI(reGional network for Acute Myocardial Infarction) project is to establish effective collaborative regional network system for STEMI patients treatment.
Detailed Description
The project of Guangdong GAMI(reGional network for Acute Myocardial Infarction) is being conducted during 2015-2019 in eight districts with diverse economic development across southern China (Integrated care model was conducted in four regions, which mainly included community public education, non primary-PCI capable centre and referral system improvement, and inhospital green-channal optimization for primary-PCI capable centre. Other four centers were underwent usual care of acute myocardial infacrtion public and medical health service). All the ST-segment elevation myocardial infarction (STEMI) patients admitted in the hospital within 30 days from the symptom onset were enrolled. The key data of the timeline of STEMI onset and treatment were precisely recorded. Other details of STEMI treatment in hospitals such as laboratory data and medication were also collected. During the research period, actions of both optimizing the regional STEMI patients transfer and treatment to shorten the medical delay, as well as educating the public to improve their awareness of early treatment of STEMI were taken meanwhile. In addition, laboratory data, medication, and follow-up information were recorded in a database for further analysis regarding the STEMI patient treatment.
Investigators
Jiyan Chen
Professor
Guangdong Provincial People's Hospital
Eligibility Criteria
Inclusion Criteria
- •All adult patients who suspected diagnosis with STEMI.
Exclusion Criteria
- •patients refused to undergo coronary angiography;
- •patients were confirmed as non-STEMI by coronary angiography or the course of STEMI over 1 month;
- •patients occurred onset STEMI during hospitalization in hospitals
Outcomes
Primary Outcomes
Receipt of reperfusion therapy within 12 hoursInfarction patients
Time Frame: From 1 month before hospitalization to 24 hours after hospitalization
The primary outcome was the proportion of patients who received symptom-to-reperfusion treatment within 12 hours.
Secondary Outcomes
- In-hospital clinical outcomes(30 days)
- 1-year all-cause mortality(1 year)
- Onset-to-admission time within 12 hours(From 1 month before hospitalization to 24 hours after hospitalization)
- Door-to-balloon time within 90 minutes(24 hours)