Investigating ELSI Issues That May Facilitate or Impede Clinical Translation of Epigenetic Research.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 1,000
- 主要终点
- Knowledge & understanding of epigenetics Information
研究概览
简要总结
Few people realize that environmental pollution and some behaviors like physical activity and tobacco smoking can affect their health by "turning on" or "turning off" certain genes through a process called "epigenetic modification." This study will develop and test strategies for communicating about epigenetics that are understandable and that do not increase ethical, legal or social issues (ELSI).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •English language speaker,
- •Identify as one of five racial/ethnic groups:
- •Non-Hispanic White
- •Non-Hispanic Black,
- •Non-Hispanic Asian
- •Non-Hispanic Indigenous (i.e., Alaska Native/Native Hawaiians/American Indian/Other Pacific Islander)
- •Hispanic (all races)
排除标准
- •Self-identify as a genetics expert
研究组 & 干预措施
Epigenetics Video
Participants will watch a brief (<5 minute) video about the concept of Epigenetics
干预措施: Epigenetics Video (Behavioral)
Individual Responsibility Video
Participants will watch a brief (<5 minute) video about the concept of Epigenetics as well as a brief (<1 minute) video discussing epigenetics and health with a focus on individual behavioral factors affecting epigenetics.
干预措施: Epigenetics Video (Behavioral)
Individual Responsibility Video
Participants will watch a brief (<5 minute) video about the concept of Epigenetics as well as a brief (<1 minute) video discussing epigenetics and health with a focus on individual behavioral factors affecting epigenetics.
干预措施: Individual Responsbility Video (Behavioral)
External Responsibility Video
Participants will watch a brief (<5 minute) video about the concept of Epigenetics as well as a brief (<1 minute) video discussing epigenetics and health with a focus on external factors affecting epigenetics.
干预措施: Epigenetics Video (Behavioral)
External Responsibility Video
Participants will watch a brief (<5 minute) video about the concept of Epigenetics as well as a brief (<1 minute) video discussing epigenetics and health with a focus on external factors affecting epigenetics.
干预措施: External Responsibility Video (Behavioral)
结局指标
主要结局
Knowledge & understanding of epigenetics Information
时间窗: Baseline survey, after intervention video
Sum score of correct answers for 11 individual items. Scale ranges from 0 points to 11 points with higher scores indicating higher epigenetics knowledge.
Acceptability of epigenetics information
时间窗: Baseline survey, after intervention video
Three constructs including perceived benefits of epigenetic research (7 items, ranging from 1 to 5 with higher scores indicating higher perceived benefits), perceived drawbacks of epigenetic research (3 items, ranging from 1 to 5 with higher scores indicating higher perceived drawbacks), and acceptance of using epigenetic research in medical support (3 items, ranging from 1 to 5 with higher scores indicating higher acceptance of using epigenetic research in medical support).
次要结局
- Perceptions of epigenetic information(Baseline survey, after intervention video)