HMG-CoA Reductase Inhibitor for postmenopausal patients used as Arterial stiffness (ASI) index ; A Phase II randomized controlled study
Phase 2
- Conditions
- Postmenopausal women (70>age >40years) with hypecholesterolemia (LDL>140mg/dl)
- Registration Number
- JPRN-UMIN000025555
- Lead Sponsor
- Obstetrics and Gynecology, Nara Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria
Not provided
Exclusion Criteria
1.familial hypercholesterolemia 2.allergy to Pravastatin 3.pregnant woman 4.hypertension 5.angina pectoris or myocardial infarction 6.stroke 7.Atrial fibrillation 8.Rheumatism 9.hepatitis or Cirrhosis of the liver 10.cancer patient
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the rate of change of ASI 1 year later after treatment
- Secondary Outcome Measures
Name Time Method the rate of change of TCHO, LDL and HDL value 1 year later after treatment