Hemodynamic Effects of Continuous Spinal Anesthesia in Patient Aged Over 65 Years Undergoing Total Knee Arthroplasty
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 20
- Locations
- 2
- Primary Endpoint
- hemodynamic profile during continuous spinal anesthesia in elderly
Study Overview
Brief Summary
Compared to single-dose spinal anesthesia, continuous spinal anesthesia using small titrated doses of local anesthetic, was safe, efficient and provided better hemodynamic profile in elderly patients.
The aim of this study was to investigate the hemodynamic effects of continuous spinal anesthesia in elderly patients undergoing knee arthroplasty.
Investigators use the FloTrac sensor/Vigileo haemodynamic monitoring system to assess modification blood pressure, stroke volume and cardiac output during anesthesia and specialy after every bolus of spinal anesthesia, after inflating the tourniquet and after putting it off.
they recorded number of hypotension episodes, ephedrine bolus and consumption until 2 hours after the end of surgery.
Detailed Description
The aim of this study was to investigate the hemodynamic effects of continuous spinal anesthesia (CSA) in elderly patients undergoing knee arthroplasty.
Inclusion criteria:
Adult patients, aged more than 65 years scheduled for elective total knee arthroplasty under regional anesthesia.
Study Design :
Patients had a transthoracic echocardiography one to three months before the surgical procedure, performed by a cardiologist.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Diagnostic
- Masking
- None
Masking Description
consecutive patient
Eligibility Criteria
- Ages
- 65 Years to 85 Years (Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Adult patients, aged more than 65 years
- •scheduled for elective total knee arthroplasty
- •under regional anesthesia
Exclusion Criteria
- •contraindication to regional anesthesia
- •or the patients who refused to give consent,
- •patients with anemia (hemoglobin < 13 g/dl for male and hemoglobin < 12 g/dl for female),
- •cardiac arrhythmias,
- •NYHA score > 2,
- •Cardiac ejection fraction < 50 %,
- •valvulopathy,
- •pulmonary artery hypertension
- •and relaxation abnormality
Outcomes
Primary Outcomes
hemodynamic profile during continuous spinal anesthesia in elderly
Time Frame: Day 0
cardiac output , L/min
Secondary Outcomes
- blood pressure variation(Day 0)
- ephedrine use(Day 0)
- stoke volume modification(Day 0)
Investigators
Olfa kaabachi, MD
professor
University Tunis El Manar