跳至主要内容
临床试验/CTRI/2024/10/074747
CTRI/2024/10/074747
尚未招募
2 期

A clinical evaluation of Dawa ul kurkum Kabir and Qurs kushta Folad in Su-al-qinya bawajah qilat Folad (Iron deficiency anemia) among women of reproductive age.

Ayurvedic and Unani Tibbia College and Hospital1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2024年10月15日最近更新:

概览

阶段
2 期
状态
尚未招募
发起方
Ayurvedic and Unani Tibbia College and Hospital
入组人数
40
试验地点
1
主要终点
Change in Hb% and PCV measured at 8wks from the baseline

概览

简要总结

The present views and reviews provides an overview on IDA in women’s health, Iron deficiency anemias high prevalence in women’s & describes the background on iron metabolism, pathogenetic mechanisms, including a focus on heavy menstrual bleeding & uterine disorders. Despite the high prevalence of IDA in reproductive aged women & it’s the impact on quality of life of women it remains undiagnosed and untreated as we focus on managing women’s heavy menstrual bleeding and uterine disorders and assume that primary care clinicians are treating the associated IDA.

We now need to take the lead in diagnosis, management and initiate early treatment for IDA in reproductive aged women’s.

Oral iron supplements (Ferric citrate, ferric maltol, ferrous fumarate, ferrous gluconate, ferrous sulfate, polysaccharide iron complexes) are well known and established remedy for IDA. However, adverse effect are abound. These include constipation or sometimes diarrhea, metallic taste, gastric irritation, and thick green tenacious stool. As previously pointed out, more than 75% of those to whom it is prescribed report significant gastrointestinal irritation.

In view of this it is the need of the present era to evaluate the efficacy of unani drugs in IDA in reproductive aged women which is safe and cost effective.

Secondly, according to the Unani concept the main cause of Su-al-qiniya is Zofe jigar and Sue mizaj jigar barid, in which hepatic processing of food becomes disturb and liver fails to prepare mature blood, instead more phlegm is formed. So with passage of time more and more phlegm accumulate in blood as well as in the body. This phlegm interfere with normal blood flow as a result nutrition as well as delivery of Arwah (pneuma) to different parts of body get disturbed. As per Unani concept adequate heat is mandatory in liver, to prepare mature khoon (humours/blood).

In reference to this Unani concept of Su-al-qiniya Dawa ul kurkum Kabir is an ancient saffron-based polyherbal formulation which is a promising unani formulation for Amraz-e-barida of Jigar, Zofe jigar and Su-al-qiniya as mentioned in Qarabadins.

For this proposed study, Dawa ul kurkum Kabir and Qurs Kushta Folad (promising iron supplement) is taken. The Purpose of this study is to generate the safety and efficacy data of the above-mentioned combined therapy in the treatment of IDA in reproductive aged women’s on modern scientific parameters.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
None

入排标准

年龄范围
15.00 Year(s) 至 45.00 Year(s)(—)
性别
Female

入选标准

  • Women of reproductive age having mild(Hb 11-11.9 hm/dl) to moderate(Hb 8-10.9gm/dl) anemia Anemia with or without heavy irregular menses Women of reproductive age(15-45yr) having complaint of Pallor, weakness, fatigue, breathlessness on exertion, palpitation, anorexia, angular stomatitis, glossitis, edema, koilonychia, dizziness and fainting.

排除标准

  • Women having Hb less than 8gm/dl and more than 11.9gm/dl Women having history of acute blood loss and chronic disease requiring long term treatment Women of age less than 15yr and more than 45yr Women having cardiovascular, renal, hepatic disease.

结局指标

主要结局

Change in Hb% and PCV measured at 8wks from the baseline

时间窗: 2 month

次要结局

  • Improvement in sign and symptoms of iron deficiency anemia(Changes in RBC count MCV, MCH, MCHC measured at 8wks from the baseline)

研究者

发起方
Ayurvedic and Unani Tibbia College and Hospital
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Mariya fatema

Ayurvedic and Unani Tibbia College and Hospital Ajmal Khan Road Karol Bagh New Delhi

研究点 (1)

Loading locations...

相似试验