Effect of hyperimmune bovine milk & colostrum in the healing process of COVID-19 patients

Phase 2

• Conditions: COVID-19.; COVID-19, virus identified; U07.1

• Registration Number: IRCT20200927048849N2
• Lead Sponsor: Isfahan university

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2021

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Infected patients of COVID-19 based on positive PCR or HRCT result compatible with disease
Hospitalization of patient in hospital
With oxygen via nasal cannula
93%=O2 Sat
Age >18years old
Filling and signing of consent form
Allowing the patient to consume food orally

Exclusion Criteria

Patients with immunodeficiency based on biography
Patients with Lactose intolerance based on biography
Uncontrollable vomit

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hospital mortality rate. Timepoint: Daily from intervention. Method of measurement: Physician approval.;Mortality rate during 28 days after the beginning of disease. Timepoint: Daily from intervention. Method of measurement: Physician approval during admission and via tell contact after discharge.;Admission rate of patient in ICU (based on hospital protocols). Timepoint: Daily from intervention. Method of measurement: Refer to the patient's file.;Days that patient needs to be hospitalized. Timepoint: Daily from intervention. Method of measurement: Refer to the patient's file.

Secondary Outcome Measures

Name	Time	Method
O2 Saturation. Timepoint: Measuring in the first day and days 3 and 5 or in the day of discharge. Method of measurement: Pulseoximetry.;Improvement rate of clinical symptoms such as dyspnea and fever. Timepoint: Measuring in the first day and days of 3 and 5 or in the day of discharge. Method of measurement: Data gathering sheet.;Erythrocytes sedimentation rate. Timepoint: Measuring in the first day and days of 3 and 5 or in the day of discharge. Method of measurement: Blood test via wester green method.;C-Reactive protein. Timepoint: Measuring in the first day and days of 3 and 5 or in the day of discharge. Method of measurement: Blood test.;Lymphocytopenia. Timepoint: Measuring in the first day and days of 3 and 5 or in the day of discharge. Method of measurement: Blood test (CBC/Diff).