Association of dry eye and clinical signs of thyroid eye disease(Thyroid associated ophthalmopathy:TAO) and prevalence of dry eye in autoimmune thyroid disease.

Not Applicable

• Conditions: Autoimmune thyroid diseaseGraves' Graves' disease; lid r; diseaseHashimoto thyroiditisThyroid status: hyperthyroid/euthyroid/hypothyroidThyroid associated ophthalmopathyDry eye syndrome; Autoimmune thyroid disease(AITD); Hashimoto thyroiditis; Dry eye syndrome; Thyroid status: hyperthyroid/euthyroid/hypothyroid; Thyroid associated ophthalmopathy(TAO)

• Registration Number: TCTR20130713001
• Lead Sponsor: Faculty of Medicine, Chulalongkorn University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-07-13
• Study Completion: 2013-09-20
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Enrolling by invitation
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Volunteers who diagnosed autoimmune thyroid dysfunction and other endocrine disease from Endocrine clinic, Department of Medicine, King Chulalongkorn Memorial hospital.

Exclusion Criteria

Volunteers documented with conditions.
1)Age of less than 20 years old
2)Pregnancy

Volunteers documented with other mostly consistence risk factor in dry eye syndrome.
1)Post-menopausal hormone therapy
2)Radiation therapy in head and neck region
3)Hematopoietic stem cell transplantation
4)Vitamin A deficiency
5)Androgen deficiency
6)Hepatitis C infection
7)LASIK & excimer laser surgery
8)Connective tissue disease
9)History of using anti-histamine in last 2 weeks

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Association of dry eye and clinical signs of TAO multiple logistic regression

Secondary Outcome Measures

Name	Time	Method
Prevalence of dry eye in AITD and TAO Prevalence rate of each parameter