Sensory processing in autism and childhood epilepsy
- Conditions
- 1002930510012562autism spectrum disorders - autism
- Registration Number
- NL-OMON44800
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 120
Ability to comply with the protocol-specified procedures for the duration of the study
IQ above 70
Written informed consent (and assent if appropriate to local laws and regulations),
In case of methylphenidate use, willingness to skip methylphenidate on the testing days
For epilepsy groups: Males and females aged 7-12, Diagnosis of epilepsy and ASD symptoms (SRS50+ or diagnosis according to ADOS, or probable/definite difference at SP-NLor behavioral problems indicative of sensory processing problems (problems at school, irritability etc)
For ASD group: Males and females aged 7-12, Diagnosis according to ADOS or given by psychiatrist
For control group: Males and females aged 7-15, No psychiatric disorder present
Major visual or auditory impairment
Presence of severe medical disorder
Other (psychiater) disorders other than epilepsy or ASD
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Primary endpoint: The main outcome parameters are EEG markers: brain evoked P50<br /><br>suppression, P300, mismatch negativity and absolute resting-state power change. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary endpoints: Other EEG phenotypes, neurocognitive and behavioural<br /><br>parameters.</p><br>