Randomized double-blind study for the effect of highly absorptive curcumin on left ventricular diastolic function in hypertensive patients with hypertrophied hearts

Phase 3

• Conditions: Hypertensive Heart Disease

• Registration Number: JPRN-UMIN000014232
• Lead Sponsor: ational Hospital Organization Kyoto Medical Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-06-11
• Study Completion: 2020-03-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up continuing
• Sex: All
• Target Recruitment: 230

Inclusion Criteria

Not provided

Exclusion Criteria

1) Chronic atrial fibrillation 2) Unstable angina, recent (< 3 months), myocardial infarction, severe coronary heart disease (left main trunk or 3 vessel disease), and recent (=< 3 months) o planned (=< 6 months) AC bypass furgery/PCI 3) Severe arrhythmia (sustained ventricular tachycardia, ventricular fibrillation, and severe bradycardia with an indication of pacemaker implantation 4) Moderate or severe valvular diseases 5) Cardiomyopathy or progressive myocarditis 6) Severe respiratory diseases 7) Cardiogenic shock or systolic blood pressure < 80 mmHg 8) Severe liver dysfunction or liver cirrhosis 9) Renal failure (Cre >=4.0 mg/dL or dialysis) 10) Recent (< 3 months) cerebrovascular disease 11) Malignancy 12) Poorly controlled diabetes (HbA1c >=8.0%) 13) Anemia (Hb < 6.0 mg.dL) 14) Use of steroid 15) Past history of curcumin allergy 16) Pregnancy, nursin g or a wish for pregnancy within next 6 months 17) etc

Study & Design

• Study Type: Interventional
• Study Design: Not specified