Comparison of Cyanocobalamin in Avocado Oil Cream With Steroid Combination Ointment

Early Phase 1

Completed

• Conditions: Plaque Psoriasis
• Interventions: Combination Product: Potent topical steroid

• Registration Number: NCT05330936
• Lead Sponsor: Pak Emirates Military Hospital

Brief Summary

A randomized clinical trial with two groups. Group A Group B Group A is being treated with conventional Steroid combination ointment for the treatment of chronic Plaque Psoriasis.

Group B is being treated with Cyanocobalamin in Avocado Oil cream for the treatment of chronic Plaque Psoriasis.

Each group having 45 patients.

Detailed Description

Outcome is being measured by PASI Score calculation with monthly follow up.

Study Timeline

• Study Start: 2021-01-01
• Study First Submitted: 2022-03-23
• Study First Submitted QC: 2022-04-10
• Study First Posted: 2022-04-15
• Primary Completion: 2022-09-01
• Study Completion: 2022-09-01
• Status Verified: 2023-05
• Last Update Submitted: 2023-05-22
• Last Update Posted: 2023-05-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• Age bracket (18-60 years)
• Non psoriatic Arthritis
• No oral Retinoids

Exclusion Criteria

• pregnancy
• Malignancy
• Body surface area involving >50%

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group B	Potent topical steroid	Cyanocobalamin in Avocado Oil cream in the treatment of chronic Plaque
Group A	Potent topical steroid	Steroid combination ointment in the treatment of chronic Plaque Psoriasis

Primary Outcome Measures

Name	Time	Method
Efficacy and tolerability of steroids as compared to Avacado Oil Cream	12 weeks	Compariaon of Efficacy of Steroid combination ointment in the treatment of chronic Plaque Psoriasis

Trial Locations

Locations (1)

PakEmiratesMH; 🇵🇰 Rawalpindi, Punjab, Pakistan