Impact of resistance training on androgen deprivation-induced adverse effects on protein metabolism, body composition and muscle function in prostate cancer patients

Blacktown Hospital0 个研究点目标入组 30 人开始时间: 2016年9月19日最近更新: 2020年1月13日

适应症

试验速览

暂无简介。

•1.ECOG less than or equal to 1; histologically confirmed prostate cancer of early or locally advanced stage, or metastatic prostate cancer with bone involvement only (less than or equal to 5 sites of bone metastases only);
•2.Plan to receive at least 12 months continuous androgen deprivation therapy by a GnRH agonist;
•3.Normal insulin sensitivity, assessed by co-investigators;
•4.Able to comprehend the requirements and procedures for the study and to provide informed consent before entering the study;

•1.Any acute condition or exacerbation of chronic conditions that in the investigators opinion would interfere with the trial visit schedule and procedures.
•2.Concurrent chemotherapy or anti-androgen therapy;
•3.Previous androgen deprivation therapy within last 12 months;
•4.Hypothalamic or pituitary disorders, cancer other than prostate cancer, diabetes mellitus and chronic renal or hepatic illnesses;
•5.Any medications known to interfere with the endocrine system (apart from ADT);
•6.People in existing dependent or unequal relationships with any member of the research team;
•7.People who may be involved in illegal activity;
•8.People highly dependent on medical care;
•9.Patients who had received an investigational new drug within the last 6 month;
•10.Patients with a cognitive impairment, an intellectual disability or a mental condition which interfere with the patient's ability to understand the requirements of the study;
•11.Inability to give written informed consent.

发起方

Blacktown Hospital