Osteoarthritis project

Not Applicable

Completed

• Conditions: Osteoarthritis (OA) of the knee; Musculoskeletal Diseases; Gonarthrosis

• Registration Number: ISRCTN16152290
• Lead Sponsor: École de Technologie Supérieure

Brief Summary

2020 Results article in https://www.ncbi.nlm.nih.gov/pubmed/31573835 results (added 03/04/2020) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36199051/ Secondary analysis (added 06/10/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-05-27
• Study Completion: 2020-03-30
• Last Update Posted: 17 October 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 515

Inclusion Criteria

1. Aged 18 or over
2. Suffering of OA of the knee as physician-diagnosed according to the criteria of the American College of Rheumatology: The patient has a radiographic knee X-ray confirming the presence of osteoarthritis II, III or IV according to the scale of Kellgren-Lawrence for at least one knee; and at least 1 of the 3 following signs: Age =40; Morning stiffness <30 minutes; Crepitus
3. OA is the leading cause of pain
4. Being able to walk on a treadmill (exclude problem of balance patient who limps, which uses cane or walker).
5. Having experienced as pain worse in the last 7 days for at least one knee, a =4/10 pain intensity on a scale of 0-10, where 0 = 'no pain' and 10 being 'worst possible pain'
6. Being able to read, understand and respond to questionnaires in French
7. Agreeing to participate in the study and sign the consent form

Exclusion Criteria

1. Suffer from secondary OA or inflammatory arthritis (according to Arden 'Best Practice & Research') or ochronosis, acromegaly, hemochromatosis, calcium pyrophosphate arthropathy (MPPC), Marfan syndrome, Ehlers-Danlos syndrome, epiphyseal dysplasia, osteonecrosis/bone infarction, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, reactive arthritis (Reiter's), gouty arthritis, SAPHO syndrome, Paget disease
2. Have seen a specialist (orthopedist, a rheumatologist or specialist in musculoskeletal disorders) in the past for problems with the affected knee
3. Suffer from active cancer (with or without pain)
4. Fracture history or septic arthritis in the knee
5. Pregnant or suspected to be

Study & Design

• Study Type: Interventional
• Study Design: Not specified