Effect of Sertraline on Schizophrenia
Not Applicable
- Conditions
- schizophrenia.The schizophrenic disorders are characterized in general by fundamental and characteristic distortions of thinking and perception, and affects that are inappropriate or blunted. Clear consciousness and intellectual capacity are usually maintained although
- Registration Number
- IRCT201110187839N1
- Lead Sponsor
- Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 54
Inclusion Criteria
1-age:16-65y/o; 2-no substance abuse or sever medical disease; 3-no pregnancy or breast feeding; 4- patients medication should be one of atypical antipsychotics(Risperidone,Olanzapine,Aripiperazole,Quetiapine or Clozapine); 5- the patients are not in acute phase of disease; 6- the patients are on maintenance medication.
Exclusion criteria:1-sever side effects; 2-no intrest in patient or his/her family to maintain on the study; 3-pregnancy; 4-drug non-tolerance.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Score of Depression. Timepoint: before starting study and after weeks 8,12. Method of measurement: CDSS(Calgray Depressive Scale of Schizophrenia).;Score of Quality of Life. Timepoint: before starting study and after weeks 8,12. Method of measurement: QLS questionare (Quality of life in Schizophrenia).;Score of Psychosis. Timepoint: before starting study and after weeks 8,12. Method of measurement: PANSS questionare (Positive And Negative Syndrome Scale).;Level of Function. Timepoint: before starting study and after weeks 8,12. Method of measurement: GAF questionare (Global Assessment of Function).
- Secondary Outcome Measures
Name Time Method Side-effects of medication. Timepoint: weeks 8,12. Method of measurement: quastionare of side effects.