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Development of an MRI scanning protocol for functional imaging of esophageal cancer.

Conditions
esophageal cancer
Registration Number
NL-OMON29032
Lead Sponsor
MC Utrecht
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
30
Inclusion Criteria

1. Patients with pathologically proven esophageal cancer referred to the department of Radiotherapy for
radiotherapy;

Exclusion Criteria

1. Glomerular Filtration Rate (GFR) of <45 mL/min/1.73m2, unless the patient has risk factors for contrast nefropathy according to the UMCU protocol ‘Preventie contrastreactie en contrast nefropathie, Versie 2 februari
2012’. In patients with risk factors a GFR of 60 mL/min/1.73m2 will be required;

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Quality of the MRI images as defined by robustness (i.e. that the protocol can successfully be applied in various patients) and geometrical accuracy. Those parameters are derived using image analysis. MR images are obtained before, during and/or after chemoradiotherapy.
Secondary Outcome Measures
NameTimeMethod
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