Inspiratory Muscle Training in Pulmonary Hypertension

Not Applicable

• Conditions: Pulmonary Hypertension

• Registration Number: NCT01410279
• Lead Sponsor: Hospital de Clinicas de Porto Alegre

Brief Summary

The purpose of this study is evaluate the effect the inspiratory muscle training on the functional capacity of patients with pulmonary hypertension.

Detailed Description

Pulmonary hypertension (PH) is a syndrome, in the case of hemodynamic alteration of a number of diseases and processes, such as the progressive increase in pulmonary vascular resistance, right heart failure and early death. Frequently patients with PH have reduced functional capacity, quality of life and survival. It was demonstrated recently that patients with HP also have inspiratory muscle weakness, possibly further increase the fatigue and dyspnea during exercise. To meet this need, inspiratory muscle training can lead to significant improvement in respiratory muscle strength, exercise tolerance and dyspnea, thus resulting in reduction of discomfort during activities of daily living, increase in exercise capacity and improved quality of life in different situations.

Study Timeline

• Study Start: 2009-12
• Study First Submitted: 2011-04-20
• Status Verified: 2011-08
• Study First Submitted QC: 2011-08-04
• Last Update Submitted: 2011-08-04
• Study First Posted: 2011-08-05
• Last Update Posted: 2011-08-05
• Primary Completion: 2011-09
• Study Completion: 2011-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

• Clinical diagnosis pulmonary hypertension
• World Health Organization (WHO) functional class II to IV
• inspiratory muscle weakness

Exclusion Criteria

• obesity
• chronic obstructive pulmonary disease
• orthopedic and neurological disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
The distance traveled in meters in the six minutes walk test after 8 weeks the inspiratory muscle training	patients will be monitored throughout the training protocol for 8 weeks

Secondary Outcome Measures

Name	Time	Method
Increase in score of quality of life questionnaire after 8 weeks the inspiratory muscle training	patients will be monitored throughout the training protocol for 8 weeks

Trial Locations

Locations (1)

Hospital de Clinica de Porto Alegre; 🇧🇷 Porto Alegre, Rio Grande do Sul, Brazil