Comparison between intraperitoneal ropivacaine alone and with Dexmedetomidine in laproscopic cholecystectomy

Completed

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2019/03/017963
• Lead Sponsor: Jln medical college Ajmer

Brief Summary

To assess the efficacy and safety of addition of dexmedetomidine to 0.25% ropivacaine used for intraperitoneal instillation on postoperative analgesia in patients undergoing laparoscopic cholecystectomy.

Primary objectives

Duration of analgesia (from the time of extubation to the demand of first dose of rescue analgesic)

Secondary objectives

Total amount of rescue analgesic required in 24 hours

Haemodynamic changes

Adverse effects, if any

Detailed Description

Not available

Study Timeline

• Study Completion: 2019-08-30
• Study Start: 2019-11-03
• Last Update Posted: 2019-11-15

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• 1.Age group between 18 years to 60 years of both sex undergoing laparascopic cholecystectomy.
• 2.Patients belonging to ASA (American Society of Anaesthesiologists) grade-I and grade-II.
• 3.Gall Bladder calculi or polyp with no evidence of acute cholecystitis at the time of surgery.

Exclusion Criteria

• 1.Age less than 18 year of age or more than 60 year of age 2.ASA grade III or more (American Society of Anaesthesiology) 3.Pregnancy 4.Acute Cholecystitis 5.Choledocolithiasis 6.Conversion of laparascopic cholecystectomy to open cholecystectomy.
• 7.patient who are allergic study drug,severe cardiac disease ,pulmonary disease, neurological disease patients in whom abdominal drain was put.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The intensity of post‑operative pain was recorded for all the cases using VAS score after surgery	Duration of the study is around 1 year
Comaprison of effect in the patients between ropivacine alone and ropivacine with dexmedetomidine	Duration of the study is around 1 year

Secondary Outcome Measures

Name	Time	Method
Total amount of rescue analgesic in 24 hours	Haemodynamic change

Trial Locations

Locations (1)

JLN Medical College Ajmer; 🇮🇳 Ajmer, RAJASTHAN, India

JLN Medical College Ajmer

🇮🇳Ajmer, RAJASTHAN, India

Dr Priyanka Soni

Principal investigator

8005708914

drpriyankasoni0@gmail.com