Effect of a Lateral Nerve of the Thigh Block on Postoperative Pain After Total Hip Replacement Surgery

Phase 4

Completed

• Conditions: Pain, Postoperative; Anesthesia, Conduction; Arthroplasty, Replacement, Hip
• Interventions: Drug: Placebo; Drug: Ropivacaine; Device: An ultrasound-guided Nervus cutaneous femoral lateralis blockade will be given postoperatively

• Registration Number: NCT02289937
• Lead Sponsor: Daniel Hägi-Pedersen

Brief Summary

The purpose of this study was to evaluate the analgesic efficacy of the nervus cutaneous femoral lateralis (NCFL) blockade on postoperative pain after total hip replacement surgery. The NCFL-block is a pure sensory block. We hypothesized that the NCFL-block would reduced the postoperative pain without delaying mobilization.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-03
• Primary Completion: 2014-10
• Study Completion: 2014-10
• Status Verified: 2014-11
• Study First Submitted: 2014-11-10
• Study First Submitted QC: 2014-11-12
• Last Update Submitted: 2014-11-12
• Study First Posted: 2014-11-13
• Last Update Posted: 2014-11-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Primary total hip replacement

Exclusion Criteria

• general anaesthesia
• Allergy to local anesthetics of the amide type
• Revision surgery
• Bilateral surgery
• Chronic pain patient
• Women in the fertile age

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Placebo	An ultrasound-guided Nervus cutaneous femoral lateralis blockade will be given postoperatively	8 ml of isotonic saline will be injected around nervus cutaneous femoral lateralis. Ultrasound-guided
Placebo	Placebo	8 ml of isotonic saline will be injected around nervus cutaneous femoral lateralis. Ultrasound-guided
Ropivacaine	An ultrasound-guided Nervus cutaneous femoral lateralis blockade will be given postoperatively	8 ml of ropivacaine 7,5 mg/ml will be injected around nervus cutaneous femoral lateralis. Ultrasound-guided.
Ropivacaine	Ropivacaine	8 ml of ropivacaine 7,5 mg/ml will be injected around nervus cutaneous femoral lateralis. Ultrasound-guided.

Primary Outcome Measures

Name	Time	Method
VAS-score 4 hours postoperative during movement	4 hours postoperative	VAS-score 4 hours postoperative during 30 degrees of flexion of the hip. VAS-score: 0-100 mm; 0: no pain, 100: worst imaginable pain.

Secondary Outcome Measures

Name	Time	Method
Oxynorm consumption	0-24 hours postoperative	Oxynorm consumption 24 hours postoperative
Mobilization	0-24 hours postoperatively	Ability to mobilize judged by the cumulated ambulation (CAS) score: 0-6; 0 no mobilization, 6: fully mobilized
Length of stay	0-7 days postoperative
VAS-score 0-24 hours postoperative during movement	0-24 hours postoperatively	VAS-score 0, 1, 2, 8, 12, and 24 hours postoperative during 30 degrees of flexion of the hip. VAS-score: 0-100 mm; 0: no pain, 100: worst imaginable pain.
VAS-score 0-24 hours postoperative at rest	0-24 hours postoperatively	VAS-score 0, 1, 2, 4, 8, 12, and 24 hours postoperative at rest. VAS-score: 0-100 mm; 0: no pain, 100: worst imaginable pain.
time to first oxynorm requirement	0-24 hours postoperatively