Role of oral methotrexate, cyclosporine and acitretin in treatment of palmoplantar psoriasis (red coloured, painful, itchy, fissured lesions on hands and feet) and psoriasis vulgaris (red coloured, scaly, itchy, elevated lesions on skin over body)

Phase 4

• Conditions: Health Condition 1: null- Palmoplantar psoriasis and psoriasis vulgaris

• Registration Number: CTRI/2015/05/005830
• Lead Sponsor: Krishna Institute of Medical Sciences Deemed University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 120

Inclusion Criteria

A.Have given written consent before any treatment commenced.

B.Be diagnosed to be suffering exclusively from Palmo-plantar psoriasis either by clinical examination or histopathology if required will be included in palmoplantar psoriasis group.

C.Be diagnosed to be suffering from psoriasis vulgaris having more than 20% body surface area will be included in psoriasis vulgaris group.

D.Have completed 18 years of age.

E.Have to stop any other modality of treatment, two months prior to the inclusion in study.

F.Be able and willing, in the view of investigator, to comply all study procedure.

Exclusion Criteria

A.Patient with hypersensitivity to drug or patient intolerant to the study medication.

B.Pregnant and lactating patient.

C.Patient with Unrealistic expectations.

D.Not willing for regular follow up.

E.Patient with clinically significant cardiovascular, haematological, pancreatic, metabolic neurological or any other laboratory anomaly, which in the judgement of investigator, would interfere in participation in study or proper evaluation.

F.Patient on any other systemic drugs therapy which in the judgement of investigator may interfere with interpretation of results.

G.Patient having history of tuberculosis or chest X-ray showing evidence of any infective pathology.

Study & Design

• Study Type: Interventional
• Study Design: Not specified