microRNA Profiles Identification in Adeno Carcinoma Prostate Cancer
- Conditions
- Prostate Carcinosarcoma
- Interventions
- Biological: High PSA levels
- Registration Number
- NCT02964351
- Lead Sponsor
- Assuta Medical Center
- Brief Summary
In our study, the investigators want to find correlation between circulating miRNAs associated with prostate cancer metastases to bones and to lymph nodes separately with results of 68Ga-PSMA ligand PET (positron emission computed) imaging.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Male
- Target Recruitment
- 120
Inclusion Criteria
- Proven Adeno-carcinoma
- Underwent prostatectomy and still present high PSA levels
- Refered to PSMA exam.
Exclusion Criteria
- Below 18 years old
- HIV/HBV (hepatitis B virus)/HCV (hepatitis C virus) positive
- Additional malignancy during the past five years.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description High PSA (prostate-specific antigen) levels High PSA levels -
- Primary Outcome Measures
Name Time Method Metastasis size and location 18 months Location of metastasis by a report analyzing the pathological examination (PET-MR output).
- Secondary Outcome Measures
Name Time Method MicroRNA profile by using Nano-string technology validated by real time PCR 24 months Validation of MicroRNA pattern by using real time PCR