Microarray Analysis of microRNA Expression in Basal Cell Carcinoma

Completed

• Conditions: Basal Cell Carcinoma

• Registration Number: NCT01498250
• Lead Sponsor: Ruhr University of Bochum

Brief Summary

Perturbations in microRNA (miRNA) expression profiles has been reported for a variety of cancers. This study will be an exploratory analysis of miRNA expression in basal cell carcinoma by miRNA expression profiling using microarrays.

Detailed Description

Perturbations in the expression profiles of microRNAs (miRNAs) have been reported for a variety of different cancers. Basal cell carcinoma (BCC) of the skin has not been systematically evaluated regarding differentially expressed miRNAs. Patients with BCC are included in the study to perform an exploratory analysis by miRNA expression profiling using microarrays. Expression levels of miRNA candidates will be validated by TaqMan real-time quantitative polymerase chain reaction (RT-PCR).

Study Timeline

• Study Start: 2011-11
• Primary Completion: 2011-12
• Study Completion: 2011-12
• Study First Submitted: 2011-12-20
• Study First Submitted QC: 2011-12-22
• Study First Posted: 2011-12-23
• Status Verified: 2012-10
• Last Update Submitted: 2012-10-15
• Last Update Posted: 2012-10-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 7

Inclusion Criteria

• Basal Cell Carcinoma

Exclusion Criteria

• Other Skin Cancer than Basal Cell Carcinoma

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum; 🇩🇪 Bochum, NRW, Germany