Optimizing Postoperative Pain Control After Laparoscopic Colorectal Surgery by Supplementing Ultrasound-guided Erector Spinae Plane Block With Ketamine or Transdermal Fentanyl Patch
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- The time to first rescue analgesia after surgery (hour)
研究概览
简要总结
Erector spinae plane block (ESPB) is a novel regional block technique that was proven to have superior outcomes in relieving postoperative pain in colorectal surgeries.Ketamine enhances the impact of local anaesthetics by reducing the duration and extent of motor block while shortening the onset of sensory and motor block.Transdermal Fentanyl Patch (TFP) was better than transdermal buprenorphine in postoperative analgesia following abdominal surgeries.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing laparoscopic colorectal surgery.
- •American Society of Anesthesiologists (ASA) physical status I or II.
排除标准
- •Known allergy to one of the study medications.
- •Skin infections at the site of the needle puncture.
- •Hepatic, renal or cardiac dysfunction.
- •Patients diagnosed with obstructive sleep apnoea
研究组 & 干预措施
Bupivacaine and ketamine
干预措施: Bupivacaine and ketamine (Other)
Bupivacaine and transdermal fentanyl patch
干预措施: Bupivacaine and transdermal fentanyl patch (Other)
Bupivacaine
干预措施: Bupivacain (Other)
结局指标
主要结局
The time to first rescue analgesia after surgery (hour)
时间窗: The first 48 hours after surgery
The time to first rescue analgesia after surgery (hour)
次要结局
未报告次要终点
研究者
Ibrahim Mamdouh Esmat
Assistant Professor of Anesthesia and Intensive Care, Faculty of Medicine, Ain- shams University, Cairo, Egypt.
Ain Shams University