A Multinational Observational Study Assessing Insulin Use: Understanding the Challenges Associated With Progression of Therapy - The MOSAIc Type 2 Diabetes Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 4,299
- 试验地点
- 1
- 主要终点
- Number of Participants With Insulin-Related Treatment Change From Initial Insulin Therapy
研究概览
简要总结
The purpose of this study is to identify specific patient, physician, and health system related factors associated with the progression to a more intensive regimen from initial insulin therapy for patients with type 2 diabetes.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Have been diagnosed with type 2 diabetes
- •Have presented within the normal course of care
- •Have been on their initial insulin therapy for ≥3 months (with or without any combination of approved non-insulin anti-diabetic medications)
- •Are not simultaneously participating in a study that includes an investigational drug or procedure at entry into the study
- •Have been fully informed and have given written consent for the use of their data
- •Have a sufficient understanding of the primary language of the country such that they will be able to complete the questionnaires
- •Have not initiated basal bolus therapy (three mealtime insulin injections)
排除标准
- 未提供
结局指标
主要结局
Number of Participants With Insulin-Related Treatment Change From Initial Insulin Therapy
时间窗: Baseline through 24 months
Multivariable logistic regression model examined baseline participant-, physician-, and healthcare system-related factors associated with the occurrence of any change in insulin therapy. Discrimination domain of the Interpersonal Processes of Care Survey \[IPC\] ranges from 1-5 with higher scores indicating more discrimination and Diabetes Distress Scale ranges from 1-6 with higher scores indicating more distress.
次要结局
- Number of Participants Who Achieved Their Personalized HbA1c Target by the End of the Study(Baseline through 24 months)
- Number of Hypoglycemic and Severe Hypoglycemic Episodes(Baseline through 24 months)
- Number of Participants Adherent to Prescribed Insulin Therapy During the Study (Study Adherent)(Baseline through 24 months)