iver Toxicity in children with HIV Infections, case controle study (LITHI study)
- Conditions
- liverdiseaselivertoxicity1001965410047438
- Registration Number
- NL-OMON35883
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Cases are 56 HIV infected children < 18 years of age that are currently being treated in Emma Children's Hospital AMC Amsterdam.
Controles are sex, ethnicity and age matched children without a HIV infection with functional abdominal pains and in whom (because of standard patient care) blooddrawings and abdominal ultrasound inevstigations are planned or healthy siblings of HIV infected children.
For both groups written informed consent is needed
Exclusion Criteria
none
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>livertoxicity</p><br>
- Secondary Outcome Measures
Name Time Method <p>n.a.</p><br>
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular pathways link HIV infection to liver toxicity in pediatric patients?
How do antiretroviral therapy regimens compare in causing liver toxicity in HIV-infected children (NL-OMON35883)?
Which biomarkers predict liver toxicity risk in children with HIV under observational studies?
What adverse event management strategies are effective for HIV-related liver toxicity in pediatric cases?
Are there alternative antiretroviral drugs with lower hepatotoxicity profiles in pediatric HIV populations?